Too easy. John Lithgow in Shrek, which also featured Mike Myers, who was in Shrek 3, which featured John Cleese, who was in How To Irritate People with TBT.

Next: Uschi Digard

I shocked myself when I realised I could do this one!

Jillie Mack appeared in an episode of Hooperman with David Rappaport...
...who appeared in (from my count) 3 episodes of the LWT season of The Goodies with TBT!

Next: John Lithgow

back again 

Bilie Joe Armstrong worked on an episode of "The Office" (US version) of which Ricky Gervais is creator. 

Ricky appeared as a guest on "Richard and Judy" as did TBT 

hmmmmm.....  who next......... how about Jillie Mack 

Damn! Some one beat me to Roxy Haji ....but will share mine anyway if that is ok 

Roxy Haji was in Spuyten Duyvil on which Jan Major was writer and co-creator.

Jan Major produced Gnarled Hollowed Road in which Mark Persky appeared. 

Mark Persky and Katharine Bailey were both in Sixteen Stories. 

Katharine went on to star in Love Actually with Emma Thompson who as we know got her start in the Cambridge Footlights as did our very own TBT 

Thank you for letting me share  - unfortunately I haven't worked out a connection for Billy Joe Armstrong - shall report back if I can get one

Cheers

Roxy Haji was in the jurior 3 with Bob Socci who was also in Babylon Fields along with William henderson White. He was in Love Monkey episode Opportunity Knocks with Judy Greer she appeared on the Sharon Osbourne show, Ozzy Osbourne was also on this show He took part in Comic Relief 2007 along with Rob brydon who we know was a guest host on I'm sorry i haven't a Clue with Tim!   

Billie Joe Armstrong

There's probably a better link than this one using TV, but I wanted to try with just movies.

Jenna Elfman was in "Doctor Dolittle"
with Paul Giamatti who was in "Fred Claus"
with Rusty Goffe who was in "Willy Wonka & the Chocolate Factory" with Timbo.

Time for a toughy:  Roxy Haji.

Naomi Watts appeared as a guest on "Richard and Judy" in 2004 as did TBT ....more than once 

NEXT: Jenna Elfman

We have the ability to hold a great deal of unnecessary (before this game) details in our heads. Does that mean we are geniuses or just bored?

When I started this game I used to do an 'overall winner' at the end of each year/round, but haven't kept track of who has been the overall winner since - probably because it was too tiring to keep score! I'd love to determine who the over-achiever is!

Anyway...Poppy Montgomery.

Poppy appeared in The Other Sister (which I remember solely because of the Savage Garden song) with Hector Elizonzo...
who was in Cuba with Maria Charles...
who was in Under The Bed (didn't I do this one in the last round?) with TBT!

Next: Naomi Watts

Wow how do you folk know all this?? You are amazing!!   

here goes
Sam Worthington and Sigourney Weaver appeared together in AVATAR.

Sigourney Weaver was a guest on Aspel and Co.  with Michael Aspel who we all know met any untimely end underneath the paw of a huge kitten in KITTEN KONG which also starred TBT 

POPPY MONTGOMERY